Protein name:
Sphingosine-1-phosphate phosphatase 1 (SPPase1;Spp1) ;
Alternative:
Sphingosine-1-phosphatase 1 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Has enzymatic activity against both sphingosine 1-phosphate (S1P) and dihydro-S1P. Regulates intracellular and extracellular S1P levels.
Subcellular Location:
Endoplasmic reticulum membrane
Multi-pass membrane protein
Protein Attributes:
50:
MSLGQRLALL | AIRLQEPQRV | ASFQRLCGVE | VPLGSPKAGE | DAETEVRGAP |
100:
GDPRRRPRQS | GADGSPAKPD | CCGAPNGVRN | GLAAEPGPTG | PRRAGSLRRN |
150:
SLTGEEGELA | KVSNLPLYYL | FCFGTELGNE | LFYIIFFPFW | IWNLDPFVGR |
200:
RLVIIWVLVM | YLGQCTKDII | RWPRPASPPV | IKLEIFYNSE | YSMPSTHAMS |
250:
GTAIPIAMIL | LTYGRWQYPL | IYGLILIPCW | SSLVCLSRIY | MGMHSILDVI |
300:
AGFLYTILIL | IIFYPLVDLI | DNFNQTYKYA | PLIIIGLHLI | LGIFSFTLDT |
350:
WSTSRGDTAE | ILGSGAGIAC | GSHAAYNLGI | SLDPSLHTLP | LAIPPLTVTL |
400:
FGKAILRVVI | GMLLVLFVRD | IMKKVTIPLA | CKLFGIPCHD | LRQARQHMEV |
430:
ELPYRYITYG | TVGFSITFLI | PYIFSFIGIS |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat SPPase1
ELISA Kit for Rat SPPase1
ELISA Kit for Rat SPPase1
Polyclonal Antibody for Rat SPPase1
Polyclonal Antibody for Rat SPPase1
Polyclonal Antibody for Rat SPPase1
Monoclonal Antibody for Rat SPPase1
Monoclonal Antibody for Rat SPPase1
Monoclonal Antibody for Rat SPPase1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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more...
Nature428:493-521(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
Brown Norway .
2.
"Rattus norvegicus sphingosine-1-phosphate phosphohydrolase (Spp1) mRNA sequence."
Yoshimura S.
,
Salomone S.
,
Waeber C.
Submitted (2000-12) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE OF 125-304
strain :
Sprague-Dawley .